CEINT's NanoPHEAT Project : Integrating Exposure and Toxicity Data to Build Risk Forecasting Tools
16 Apr 2020
The NanoPHEAT tool (Nano Product Hazard and Exposure Assessment Tool) is built to compile dose-response curves from literature, including hundreds of papers, and calculates the estimated exposure to nanoparticles as released from real products, based on some in-house experimental values that we...
Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics
20 Jun 2019
Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...
Transitioning to Predictive Analysis for Nanoparticle Biocorona Studies
14 May 2019
Nano WG April 18, 2019: Proteins adsorbed to nanomaterials in a biological environment mediate cellular recognition, uptake, and toxicity of nanomaterials. Here, Dr. Korin Wheeler presents the development of experimental methods to characterize this population of proteins (also...
Accelerating Nanotech Innovations Through a Safer-By-Design Approach, Safer Nanomaterials School
14 May 2019
Nano WG May 9, 2019European Scientific Institute (ESI) Safer Nanomaterials School Introduction.
The history of chemical information and the materials of the future
25 Apr 2019
Techniques, technologies, cultures, and infrastructures of information management played a central role in the development of the modern chemical sciences and the global chemicals industry since the late 19th century. Chemical databases and analytical techniques that privileged abstract,...
FAIR for NanoSafety: where do we stand?
05 Apr 2019
Nano WG April 4, 2019 Findable, Accessible, Interoperable, Reusable (FAIR) sharing of nanosafety data.
Development of Targeted Nanomedicines via Machine Learning Processes
05 Mar 2019
Nano WG February 21, 2019Description: We are using data science to facilitate the development of nanoparticle drugs incorporating kinase inhibitors with diverse chemical structures. Doing this work inspired us to bring together the nanoinformatics community...
Development of natural language processing tools for nanoparticle design
05 Mar 2019
Nano WG February 28, 2019: In this presentation, an introduction to the application of natural language processing techniques to nanotechnology data will be discussed. Natural language processing tools can aid in the automatic categorization, extraction, and analysis of data from...
Dataset Curation, Assessment of their Quality, and Prediction Model Developments for Safe and Sustainable Nanotechnology (S2NANO)
29 Nov 2018 | Presentations
Nano WG November 29, 2018: Tae Hyun Yoon, Prof./CEO/Ph.D., Yoon Idea Lab. Co. Ltd. & Hanyang University In this presentation, I will introduce our recent research outcomes from S2NANO: PredictNANO project, which aimed to bridge the nanosafety knowledge gaps between R&D...
NCI Alliance for Nanotechnology in Cancer, and caNanoLab: A Data Repository for Cancer Nanomedicines
27 Nov 2018 | Presentations
Nano WG presentation November15, 2018 NCI Alliance for Nanotechnology in Cancer –Structure–Achievements–Scientific FocuscaNanoLab–Intro to Platform–Data Curation–User Statistics–Future Directions
NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation
11 Jul 2018 | Presentations
Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...
Dissolution as a Paradigm in Regulating Nanomaterials
16 Aug 2017 | Presentations
Nano WG presentation, August 10, 2017 Themes: • Dissolution as a decision criterion • Analogies to ζ-potential & VSSA • Relation to nanoform & nanoscale form • Dissolution kinetics and artifacts • ASTM particle ontology & Nanoinformatics Roadmap...
15 Aug 2017 | Publications | Contributor(s): Sumudinie fernando, Ann Christine Catlin
Collated tweets from workshop and networking reception.
05 Jul 2017 | Presentations
General Overview of the caNanoLab data portal: data submission workflow, collaboration features, data sharing and working with Journals and PubMed to share information about data submissions.
NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting
26 May 2017 | Presentations | Contributor(s): Sumudinie fernando, Ann Christine Catlin
Nano WG presentation on May 25, 2017. Presentation by Dr. Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents
European Chemical Agency's work to implement REACH regulation for nanomaterials
04 May 2017 | Presentations
Nano WG presentation on May 4, 2017. REACH = Registration, Evaluation, Authorisation (& restriction) of Chemicals aims to ensure a high level of protection of human health and the environment while enhancing competitiveness and innovation. Nano materials are covered by...
Human Disease Ontology
21 Sep 2016 | External Applications | Contributor(s): Sumudinie fernando, Ann Christine Catlin
The Disease Ontology has been developed as a standardized ontology for human disease, since 2003, with the purpose of providing the biomedical community with manual curated, consistent, reusable and sustainable descriptions of human disease terms, phenotype characteristics and related...
Summary of the 2015 Epigenetic Engineering for Cancer Workshops
22 Dec 2015 | Publications | Contributor(s): Sumudinie fernando, Ann Christine Catlin
This document provides a general summary of the 2 virtual workshops held in Fall of 2015 to explore the suitability of epigenetic engineering tools to specifically modify epigenetic loci to study and/or treat cancer.
Introduction to the Trinity Cancer Transcriptome Analysis Toolkit
05 Feb 2015 | Teaching Materials | Contributor(s): Sumudinie fernando, Ann Christine Catlin
This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes. Visit our NCGAS Trinity/Galaxy portal to access these compute...
Multiclass cancer diagnosis using tumor gene expression signatures
10 Nov 2014 | Downloads | Contributor(s): Sumudinie fernando, Ann Christine Catlin
Experiment Description: The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...