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  1. HUBzero: A platform for dissemination and collaboration in Computational Science and Engineering

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    07 Aug 2015 | Contributor(s): Michael McLennan, Rick Kennell

    The HUBzero cyberinfrastructure lets scientific researchers work together online to develop tools. Other researchers can then access the resulting tools using an ordinary Web browser and launch simulation runs on the national Grid infrastructure, without having to download or...

  2. HUBzero: A Web-based Platform for research, Education and Scientific Collaboration

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    11 Sep 2013 | Presentations | Contributor(s): Michael McLennan

    Imagine an app store for scientists, engineers, and educators filled with simulation and modeling tools — not simple Java applets, but real research codes that tackle difficult problems and may require substantial computing power drawn from the Cloud. Imagine a new way of publishing...

  3. Informatics to enable Routine Personalized Cancer Therapy (IPCT)

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    18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam

  4. Informatics Tools for High-throughput Analysis of Cancer Mutations

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    15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin

  5. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

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    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  6. Integrative Cancer Biology Program Datasets

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    26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

    The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

  7. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

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    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  8. ITCR Monthly Teleconference September 4, 2015

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    07 Oct 2015 | Presentations | Contributor(s): Juli Klemm

     

  9. ITCR PI Meeting June 2014 Presentations

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    23 Jun 2014 | Series

    Informatics Technology for Cancer Research (ITCR) Initiative held its Annual PI Meeting on June 12-13, 2014 in Rockville, MD. This series contains the presentations given at the meeting.

  10. Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics

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    20 Jun 2019 | Presentations | Contributor(s): Haralambos Sarimveis

    Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...

  11. LBL ICBP50 integrative genomic data

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    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  12. Life after MOOCS: Online Science Education Needs a New Revolution

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    03 Feb 2017 | Presentations | Contributor(s): Phillip Compeau

    ITCR Monthly PI Meeting, February 3, 2017 Presentation by Phillip Compeau (Carnegie Mellon U.)

  13. NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation

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    11 Jul 2018 | Presentations | Contributor(s): Jaleesia Amos, Yuan Tian, Mervi Heiskanen

    Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...

  14. Next-Generation Clustered Heat Maps (NG-­CHM)

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    07 Oct 2015 | Presentations | Contributor(s): Weinstein John, Bradley Broom

    Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...

  15. Notes from the ITCR Annual Meeting May 27-28, 2015

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    10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm

    Notes from the ITCR Annual Meeting May 27-28, 2015

  16. Open source diffusion MRI technology for brain cancer research

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    07 Oct 2015 | Presentations | Contributor(s): Lauren O\'Donnell

    Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...

  17. Overview on HUBzero - Building Scientific Communities Online

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    03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan

    This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.

  18. Pathology Image Informatics Platform for visualization, analysis and management

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    07 Oct 2015 | Presentations | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel

    This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...

  19. Providing National Cyberinfrastructure to Biologists, esp. Genomicists

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    02 Sep 2016 | Presentations | Contributor(s): Tom Doek, Mervi Heiskanen

    National Center for Genome Analysis Support (NCGAS) provides access to High Performance Computing resources for biologists. NCGAS also maintains a curated set of applications and Galaxy instances of their software, as well as provides bioinformatics expertise.

  20. QIN HUBzero update

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    28 Oct 2013 | Teaching Materials | Contributor(s): Jayashree Kalpathy-Cramer

    presentation for the QIN EC meeting 10/21/2013