-
Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
-
Integrative Cancer Biology Program Datasets
26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich
The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...
-
Introduction to the Trinity Cancer Transcriptome Analysis Toolkit
05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett
This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes. Visit our NCGAS Trinity/Galaxy portal to access these compute...
-
Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics
20 Jun 2019 | Presentations | Contributor(s): Haralambos Sarimveis
Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...
-
LBL ICBP50 integrative genomic data
13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline
From Joe Gray, Lawrence Berkeley National Laboratory. There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...
-
Multiclass cancer diagnosis using tumor gene expression signatures
10 Nov 2014 | Downloads
Experiment Description: The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...
-
NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting
26 May 2017 | Presentations | Contributor(s): Shivani Sharma
Nano WG presentation on May 25, 2017. Presentation by Dr. Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents
-
NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation
11 Jul 2018 | Presentations | Contributor(s): Jaleesia Amos, Yuan Tian, Mervi Heiskanen
Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...
-
Patient Stories
30 Nov 2015 | Teaching Materials | Contributor(s): Diane Townsel
Beaumont’s Patient videos: is the story of five patients that have participated in clinical research or have been a part of a bio-specimen study. The videos tell the unique stories of our patients and how our Cancer Clinical Trials staff build relationships with our patients and guide them...
-
Por Nuestras Hijas/For Our Daughters HPV Program
24 Nov 2015 | Teaching Materials | Contributor(s): Maria E. Fernandez
The Por Nuestras Hijas/For Our Daughters HPV program is an interactive, culturally appropriate HPV education program which includes a print fotonovela and a tailored interactive multimedia intervention (TIMI). The TIMI runs on iPads and also available on the web and mobile platforms. The program...
-
Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment
18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar
Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...
-
Summary of the 2015 Epigenetic Engineering for Cancer Workshops
22 Dec 2015 | Publications | Contributor(s): Tony Dickherber
This document provides a general summary of the 2 virtual workshops held in Fall of 2015 to explore the suitability of epigenetic engineering tools to specifically modify epigenetic loci to study and/or treat cancer.
-
Text Messaging and Phone Calls as Tools to Promote Healthy Behaviors among Hispanic Populations
24 Nov 2015 | Teaching Materials | Contributor(s): Laura Leticia Nervi, Barbara Damron, Maria Otero, Andrew Sussman, Dolores Guest
Title: Text Messaging and Phone Calls as Tools to Promote Healthy Behaviors among Hispanic Populations Objectives: The primary aim of this project was to evaluate the use of text messaging and phone calls to motivate Hispanic adult males and females to increase their daily physical...
-
Text Messaging as a Method to Increase Oral Chemotherapy Adherence in Hispanic Cancer Populations
23 Nov 2015 | Teaching Materials | Contributor(s): Laura Leticia Nervi, Barbara Damron, Andrew Sussman, Dolores Guest
Title: Text Messaging as a Method to Increase Oral Chemotherapy Adherence in Hispanic Cancer Populations: Patient and Provider Feasibility Surveys Objectives: The purpose of this study was to explore the feasibility of conducting an interventional study to evaluate the effectiveness of text...
-
The Boston Medical Center Patient Navigation Toolkit
22 Dec 2015 | Downloads
The BMC Toolkit offers case studies, tools and resources from cancer care navigation that can be applied to reduce the impact of the target disease, health disparities, and barriers to care unique to your own community. For Program Planners, Volume 1: Developing your Patient Navigation...
-
The history of chemical information and the materials of the future
25 Apr 2019 | Presentations | Contributor(s): Evan Hepler-Smith
Techniques, technologies, cultures, and infrastructures of information management played a central role in the development of the modern chemical sciences and the global chemicals industry since the late 19th century. Chemical databases and analytical techniques that privileged abstract,...
-
Transitioning to Predictive Analysis for Nanoparticle Biocorona Studies
14 May 2019 | Presentations | Contributor(s): Korin Wheeler
Nano WG April 18, 2019: Proteins adsorbed to nanomaterials in a biological environment mediate cellular recognition, uptake, and toxicity of nanomaterials. Here, Dr. Korin Wheeler presents the development of experimental methods to characterize this population of proteins (also...
-
Understanding Colorectal Cancer to Protect our Communities
24 Nov 2015 | Teaching Materials | Contributor(s): NCI
This is a teaching material originally developed by NCI.
-
Workshop Tweets
15 Aug 2017 | Publications | Contributor(s): Stephanie Morris
Collated tweets from workshop and networking reception.