The ‘Center for Genomic Pathology’ is devoted to integrating the structure of disease in animal models with the molecular biology and physiology of the disease.
Our Premise: The structural basis of disease is best identified by qualified anatomic pathologists. Accurate phenotyping of disease models requires understanding of mouse biology, comparative pathology, and molecular pathology and biology. Challenge: To provide the scientific community the services of qualified, expert pathologists.
1. HARMONIZATION (STANDARDIZATION): To insure that anatomic pathology provides uniform interpretable reporting of results:
a. TECHNICAL: Reproducible, reliable, and standardized techniques in each laboratory.
b. NOMENCLATURE (VOCABULARY): The terms used are universally applied and synonym recognized.
c. INTERPRETATION: The same slides are interpreted the same in all venues. Or, the basis for the differences in interpretation is understood.
2. ‘EDUCATION‘ (CERTIFICATION): To provide widespread training at minimal cost.
a. Training Courses: Distance learning saves resources and provides basic information to (Level 1) technical staff, students, fellows, (Level 2) principal investigators, and (Level 3) pathologists. Leads to certification.
b. TRAINING WORKSHOPS: Hands on workshops at three levels for all levels. Required at the technical level. Leads to certification.
c. Continuing Education: Periodic educational reinforcement and updating. Access to Image Archives and other resources. Leads to documentation.
3. VERIFICATION (VALIDATION): To determine that the interpretations of results are acceptable. To provide advice when local expertise is not available.
a. PANELS OF EXPERTS: Access to organized groups of experts who can verify interpretations and discuss problem areas.
b. CERTIFICATION OF INDIVIDUAL EXPERTISE: The development of expertise requires broad exposure to pathology that is frequently not available in local venues. Online training programs for qualified pathologists can supplement local resources.
c. CONSULTATION: Consult with expert, experienced pathologists BEFORE the experiment is designed or executed. Learn what to do and how to do it before it is too late.
1. COMMUNICATION (INFORMATICS)
a. INTEGRATION AND ORGANIZATION OF DATA
c. INTERNATIONAL INFORMATICS STANDARDS
2. ORGANIZATION AND CURATION
a. COOPERATIVE CONSORTIA
b. CURATOR OF ONLINE RESOURCES
3. HARMONIZATION: CORE LABORATORY
Financial Support: Dependent upon international core support using cooperative/federated models. Coordination should utilize existing organizations and resources. CURRENT EDUCATIONAL TOOLS:
The Center for Genomic Pathology (http://www.ctrgenpath.net) offers online training courses in Mouse Pathobiology designed for graduate students, lab technicians, residents, scientists and pathologists interested in learning more about genetically engineered mouse models. Entire semester, or short course learning modules are available for CE, CME and Career Development. These courses in Comparative Pathology are offered via the UC Davis Extension program.
Two of the offered E-Learning courses received the UPCEA Outstanding Distance Learning Award: Tier 1A (2010) & Tier 1B (2011). Tier 2 is offered to advanced students and principle investigators with organ-specific or special interests. .
The CGP hosts monthly teleconferences where participants submit case slides for real-time discussion and expert opinion. Specimens can submitted to the HistoPathology Core, and information can be shared remotely via our secure database (Spectrum).
JOIN OUR INTEREST GROUP HERE: http://linkd.in/1hwHGJ9
Submit specimens to our HISTOPATHOLOGY LAB by visiting http://spectrum.ucdavis.edu and following the instructions provided.
View our Score-the-Core 2 Training tool: http://cgp.ucdavis.edu/athena_test . Feel free to register and begin honing your skills.
Whole slide images from the MMHCC consensus conferences: http://bit.ly/1l1lhEB