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  1. Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

    18 Aug 2015 | Contributor(s): Odemaris Narvaez del Pilar

    Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

  2. Support Access to NPO's Structure and Content

    13 Aug 2015 | Contributor(s): Michael Halper, Vladimir Ventura, Yehoshua Perl

    •Abstraction Networks (“AbNs”) for Ontologies•Two example AbNs:–Area taxonomy–Partial-area taxonomy•BLUOWL: taxonomy-based software tool•Application to the NPO•Conclusions

  3. Data Readiness Levels

    13 Aug 2015

    Nanotechnology Signature InitiativeNanotechnology Knowledge Infrastructure (NKI):Enabling National Leadership in Sustainable DesignDraft Discussion Document: May 9, 2013

  4. A Brief History of OpenTox

    25 Jun 2015 | Presentations | Contributor(s): Barry Hardy

    Nano WG June 25, 2015 The history and challenges of OpenTox developments and the potential of its community, framework and principles applied to advancing safety assessment goals.  

  5. Molecule & Particle Differentiation Using Electrophoresis

    28 Apr 2015 | Presentations | Contributor(s): Frederick C. Klaessig, Sharon Ku

    Nano WG April 16, 2015

  6. Nanoinformatics Workshop 2015

    23 Mar 2015 | Presentations | Contributor(s): Mark Tuominen, Mervi Heiskanen

    Nano WG March 19, 2015.

  7. Why in the world do we need a nanomaterials description system – How CODATA and VAMAS answers that question

    12 Mar 2015 | Presentations | Contributor(s): John Rumble

    Nano WG March12, 2015

  8. So What Can We Do With Nano Informatics? – Leveraging Decision Analytic Tools

    22 Jan 2015 | Presentations | Contributor(s): Igor Linkov, Matthew Bates

    Jan 22, 2015 meeting                  Nanotechnology Working Group Matthew E. Bates & Igor Linkov Risk & Decision Science Team Environmental Laboratory, Engineer Research and Development Center, US Army...

  9. Some Thoughts on Reproducibility

    05 Dec 2014 | Presentations | Contributor(s): John Rumble

    Nano WG December 4, 2014

  10. Some Thoughts on Reproducibility

    05 Dec 2014 | Presentations | Contributor(s): John Rumble

    Nano WG December 4, 2014

  11. Data, Metadata and "Data Quality" for Databases

    05 Dec 2014 | Presentations | Contributor(s): Frederick C. Klaessig, Mervi Heiskanen

    Nano WG December 4, 2014

  12. Data, Metadata and "Data Quality" for Databases

    05 Dec 2014 | Presentations | Contributor(s): Frederick C. Klaessig, Mervi Heiskanen

    Nano WG December 4, 2014

  13. Data Reproducibility Nanotechnology Knowledge Infrastructure Data Curation

    05 Dec 2014 | Presentations | Contributor(s): Martin Fritts

    Nano WG presentation on December 4, 2014

  14. Data Reproducibility Nanotechnology Knowledge Infrastructure Data Curation

    05 Dec 2014 | Presentations | Contributor(s): Martin Fritts

    Nano WG presentation on December 4, 2014

  15. LBL ICBP50 integrative genomic data

    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  16. Baylor Residual breast cancer

    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  17. Overview of the National Cancer Institute (NCI) Nanotechnology Characterizaton Laboratory (NCL)

    03 Nov 2014 | Presentations | Contributor(s): Jennifer Hall Grossman

    Working in concert with the National Institute of Standards and Technology (NIST) and the U.S. Food and Drug Administration (FDA), the National Cancer Institute (NCI) established the Nanotechnology Characterization Laboratory to perform preclinical efficacy and toxicity testing of...

  18. caNanoLab Data Portal Presentation

    25 Sep 2014 | Presentations | Contributor(s): Sharon Gaheen

    caNanoLab is a data sharing portal designed to facilitate information sharing across the international biomedical nanotechnology research community to expedite and validate the use of nanotechnology in biomedicine. caNanoLab provides support for the annotation of nanomaterials with...

  19. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  20. Environmental Consequences of Nanotechnologies

    11 Sep 2014 | Presentations | Contributor(s): Jeffrey Steevens, Alan Kennedy, Jessica Coleman, Zach Collier, Aimee Poda, Charles Weiss, Mark Widder, Jonathan Stallings, Robert Moser

    Jeffery A Steevens, Senior ScientistAlan Kennedy, Jessica Coleman, Zach Collier, Robert Moser, Aimee Poda, Charles WeissUS Army ERDCMark Widder and MAJ Jonathan StallingsUS Army Center for Environmental Health ResearchPresentation to NCI - Nanotechnology Working Group 11 September 2014