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  1. Pathology Image Informatics Platform for visualization, analysis and management

    07 Oct 2015 | Contributor(s): Metin Gurcan, Anant Madabhushi, Anne Martel

    This multi-institutional proposal seeks to expand on an existing, freely available pathology image viewer (Sedeen Image Viewer) to create a pathology informatics platform (PIIP) for managing, annotating, sharing, and quantitatively analyzing digital Pathology Imaging (DPI) data. Sedeen has become...

  2. Next-Generation Clustered Heat Maps (NG-­CHM)

    07 Oct 2015 | Contributor(s): Weinstein John, Bradley Broom

    Clustered Heat Maps (CHMs) have been referred to as the ubiquitous visual icons of post-genomic biology -- the most frequent type of visualization for large molecular profiling databases. However, “traditional” CHMs are static images -- a serious limitation. Accordingly, we have now...

  3. Open source diffusion MRI technology for brain cancer research

    07 Oct 2015 | Contributor(s): Lauren O\'Donnell

    Using measurements of water diffusion, dMRI can give unique insights into the microstructure and cellular orientation of tissues. There is a growing awareness in the neurosurgery community that diffusion models must move beyond the current clinical standard of the diffusion tensor for better...

  4. ITCR Monthly Teleconference September 4, 2015

    07 Oct 2015 | Contributor(s): Juli Klemm

     

  5. Brain Cancer Imaging Analytics

    02 Oct 2015 | Presentations | Contributor(s): Christos Davatzikos

    The transition of oncologic imaging from its “industrial era” to it is “information era” demands analytical methods that 1) extract information from this data that is clinically and biologically relevant; 2) integrate imaging, clinical, and genomic data via rigorous...

  6. Data Readiness Levels

    13 Aug 2015 | Teaching Materials

    Nanotechnology Signature InitiativeNanotechnology Knowledge Infrastructure (NKI):Enabling National Leadership in Sustainable DesignDraft Discussion Document: May 9, 2013

  7. Trinity: RNA-Seq De novo Assembly Application

    30 Jun 2015 | External Applications | Contributor(s): Grabherr MG, Brian Haas, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, Di Palma F, Birren BW, Nusbaum C, Lindblad-toh K, Friedman N, Regev A

     Quick Guide for the ImpatientTrinity assembles transcript sequences from Illumina RNA-Seq data.Download Trinity here.Build Trinity by typing make : ; in the base installation directory.Assemble RNA-Seq data like so:Trinity --seqType fq --left reads_1.fq --right reads_2.fq...

  8. CRAVAT - Cancer-Related Analysis of Variants Toolkit

    23 Jun 2015 | External Applications | Contributor(s): Rachel Karchin, Michael C Ryan

    cravat is a bioinformatics pipeline : ; that performs high-throughput cancer-related analysis of variants. it : ; utilizes three applications: CHASM (Cancer-Specific Analysis of Somatic Mutations), VEST and SVN-Get. More information on these tools is available at CHASM Software.Release...

  9. Tools for Creation of Integrated Data Repository for Cancer Research

    16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang

    Admin Supplement Proposal Parent Projects: DeepPhe (PIs: Savova and Jacobson) caCDE-QA (PI: Jiang)

  10. A Semantic Web-based Quality Assurance Tool for Cancer Study Common Data Elements

    16 Jun 2015 | Presentations | Contributor(s): Guoqian Jiang

    A poster presentation from the caCDE-QA project (PI: Jiang)  

  11. Notes from the ITCR Annual Meeting May 27-28, 2015

    10 Jun 2015 | Downloads | Contributor(s): Ishwar Chandramouliswaran, Juli Klemm

    Notes from the ITCR Annual Meeting May 27-28, 2015

  12. Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

    05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

    This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

  13. Some Thoughts on Reproducibility

    05 Dec 2014 | Presentations | Contributor(s): John Rumble

    Nano WG December 4, 2014

  14. Data, Metadata and "Data Quality" for Databases

    05 Dec 2014 | Presentations | Contributor(s): Frederick C. Klaessig, Mervi Heiskanen

    Nano WG December 4, 2014

  15. Data Reproducibility Nanotechnology Knowledge Infrastructure Data Curation

    05 Dec 2014 | Presentations | Contributor(s): Martin Fritts

    Nano WG presentation on December 4, 2014

  16. CRAVAT Introduction Video - Cancer Related Analysis of Variants

    03 Dec 2014 | Teaching Materials | Contributor(s): Michael C Ryan

    This video provides a brief overview of the CRAVAT web service(http://www.cravat.us/).  CRAVAT provides annotation and analysis of cancer mutations. CRAVAT is free, very easy to use, and can handle large volumes of mutations.[[Youtube(xovmIy11Bcs)]]Please switch to 1080 resolution and watch...

  17. Analysis, integration and visualization of DNA methylation sequencing data

    07 Nov 2014 | Presentations | Contributor(s): Maureen Sartor

    Integrative epigenomic/genomic profiling and biomarker discovery of HPV+ and HPV- squamous cancers.

  18. Summarization of Big Data

    07 Nov 2014 | Presentations | Contributor(s): Jeffrey A. Blimes

    All about assay selection...

  19. Overview of the National Cancer Institute (NCI) Nanotechnology Characterizaton Laboratory (NCL)

    03 Nov 2014 | Presentations | Contributor(s): Jennifer Hall Grossman

    Working in concert with the National Institute of Standards and Technology (NIST) and the U.S. Food and Drug Administration (FDA), the National Cancer Institute (NCI) established the Nanotechnology Characterization Laboratory to perform preclinical efficacy and toxicity testing of...

  20. Biomedical Evidence Graph

    03 Oct 2014 | Presentations | Contributor(s): Josh Stuart