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Integrated analysis of breast cancer cell lines reveals unique signaling pathways
16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman
AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...
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Environmental Consequences of Nanotechnologies
11 Sep 2014 | Presentations | Contributor(s): Jeffrey Steevens, Alan Kennedy, Jessica Coleman, Zach Collier, Aimee Poda, Charles Weiss, Mark Widder, Jonathan Stallings, Robert Moser
Jeffery A Steevens, Senior ScientistAlan Kennedy, Jessica Coleman, Zach Collier, Robert Moser, Aimee Poda, Charles WeissUS Army ERDCMark Widder and MAJ Jonathan StallingsUS Army Center for Environmental Health ResearchPresentation to NCI - Nanotechnology Working Group 11 September 2014
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Considerations of relevance vs reliability and know vs show for CLEAR communication and how they relate to issues for nanotechnology, including the data-readiness levels
09 Sep 2014 | Presentations | Contributor(s): Stacey L Harper, Mark D Hoover
Presentation for the Nano WG 4.24. 2014
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Data Readi
13 Aug 2014 | Teaching Materials | Contributor(s): Lisa E Friedersdorf
Nanotechnology Signature InitiativeNanotechnology Knowledge Infrastructure (NKI):Enabling National Leadership in Sustainable DesignDraft Discussion Document: May 9, 2013
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Nanocuration update by Christine Hendren
02 Jun 2014 | Presentations | Contributor(s): Christine Ogilvie Hendren
Nanocuration update by Christine Hendren, Nano WG May 29, 2014
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Informatics to enable Routine Personalized Cancer Therapy (IPCT)
18 Feb 2014 | Presentations | Contributor(s): Elmer V. Bernstam, Funda Meric-Bernstam
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Advanced Development of TIES - A Clinical Text Search Engine
18 Feb 2014 | Presentations | Contributor(s): Rebecca Crowley
Archived human tissues are an essential resource for translational research. Formalin-fixed, paraffin-embedded (FFPE) tissues from cancer patients are used in a wide range of assays, including RT-PCR, SNP profiling, multiplex biomarkers, imaging biomarkers, targeted exome, whole exome, and whole...
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Informatics Tools for High-throughput Analysis of Cancer Mutations
15 Jan 2014 | Presentations | Contributor(s): Michael C Ryan, Rachel Karchin