Integrated analysis of breast cancer cell lines reveals unique signaling pathways

16 Sep 2014 | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

Integrative Cancer Biology Program Datasets

26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

Introduction to the Trinity Cancer Transcriptome Analysis Toolkit

05 Feb 2015 | Teaching Materials | Contributor(s): Brian Haas, Aviv Regev, Bill Barnett

This short video provides an overview of our ITCR-funded effort to leverage RNA-Seq and de novo transcriptome assembly to assist researchers in studying cancer transcriptomes.  Visit our NCGAS Trinity/Galaxy portal to access these compute...

Jaqpot - An open-source web platform for creating, using, testing and sharing predictive models in nano-informatics

20 Jun 2019 | Presentations | Contributor(s): Haralambos Sarimveis

Nano WG June 20, 2019Computational models that predict physicochemical properties, biokinetics or adverse biological effects of Engineered Nanomaterials (ENMs) are becoming increasingly important to support risk assessment and safety-by-design. This is primarily due to cost-saving and...

LBL ICBP50 integrative genomic data

13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

Multiclass cancer diagnosis using tumor gene expression signatures

10 Nov 2014 | Downloads

Experiment Description:    The optimal treatment of patients with cancer depends on establishing accurate diagnoses by using a complex combination of clinical and histopathological data. In some instances, this task is difficult or impossible because of atypical clinical...

NANOANALYTICS OF EXTRACELLULAR VESICLES – Standards for isolation, characterization and reporting

26 May 2017 | Presentations | Contributor(s): Shivani Sharma

Nano WG presentation on May 25, 2017. Presentation by Dr.  Shivani Sharma, Associate Director of the Nano Pico Characterization Lab, UCLA. Nanoscale characterization of exosomes and their use disease biomarkers and drug delivery agents

NanoInformatics Knowledge Commons Curation Team: Building the Data Dictionary to Enrich Data Curation

11 Jul 2018 | Presentations | Contributor(s): Jaleesia Amos, Yuan Tian, Mervi Heiskanen

Nano WG Presentation, May 31st, 2018 Organized storing of data using informed-decision making to determine what information should be curated, when data curation is complete, and how to identify high-quality data. Purpose of NIKC structure & curation process: tell the story of...

NCIP Hub QIN Workshop - March 3, 2015

19 Mar 2015 | Presentations | Contributor(s): Michael McLennan

Mike McLennan, director of HUBzero, presented an overview of basic NCIP Hub functionality to the QIN group on March 3, 2015. The presentation included an overview of the "hub" and HUBzero, and touched upon functionality such as projects, groups, resources and information sharing. The...

Overview on HUBzero - Building Scientific Communities Online

03 Sep 2013 | Teaching Materials | Contributor(s): Michael McLennan

This is a white paper/publication on the HUB and how one can build online communities using the HUBzero platform. See the tab on supporting documents for a video presentation.

Overview: The HUBzero Platform for Scientific Collaboration

18 Dec 2013 | Presentations | Contributor(s): Michael McLennan

This web site was created using a collaborative infrastructure called HUBzero, developed by Purdue University. HUBzero is the basis of nanoHUB.org and more than 50 other sites covering a wide range of scientific disciplines, including bio-fuels, microelectromechanical systems, cancer research,...

QIBA Status

21 Apr 2014 | Presentations | Contributor(s): Daniel Sullivan, Vyshak Chandra

Status and potential for further collaboration with RSNA QIBA

QIN HUBzero update

28 Oct 2013 | Teaching Materials | Contributor(s): Jayashree Kalpathy-Cramer

presentation for the QIN EC meeting 10/21/2013

QIN Tools Inventory Summary

15 Oct 2014 | Teaching Materials | Contributor(s): Andrey Fedorov

QIN Tools survey has been conducted in two iterations starting from the Spring 2014 [1]. In the beginning of Summer 2014, a revised version of the survey has been released [2]. The results of the survey are available at [3], and also include the analysis of other data sources (such as “QIN...

Quantitative Image Informatics for Cancer Research (QIICR)

04 Apr 2014 | Presentations | Contributor(s): Andrey Fedorov, Ron Kikinis

Quantitative Imaging Network (QIN) in China

18 Apr 2014 | Presentations | Contributor(s): Yan Kang

A presentation on challenges & opportunities for QIN in China