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  1. Shutter-Speed Model DCE-MRI for Assessment of Response to Cancer Therapy

    30 Apr 2014 | Teaching Materials | Contributor(s): Wei Huang, Christopher Ryan

  2. Evaluation of HCC Response to Systemic Therapy with Quantitative MRI

    30 Apr 2014 | Teaching Materials | Contributor(s): Guido Jajmovich, Octavia Bane, Hadrien Dyvorne, Bachir Taouli

    Overall objective: Develop a quantitative multiparametric protocol combining measurements of MR diffusion, perfusion and hypoxia in hepatocellular carcinoma (HCC)

  3. Prognostic Value of Tumor Hypoxia, as measured by 18F-FMISO Breath-Hold PET/CT, in NSCLC

    30 Apr 2014 | Teaching Materials | Contributor(s): S.A. Nehmeh, J. Schwartz, R. Schmidtlein, H. Schoder, A. Rimner, J. Chaft, M. Grkowski, J. Humm

  4. RADIOMICS ON LUNG CANCER

    30 Apr 2014 | Teaching Materials | Contributor(s): Robert Gillies, Robert Gatenby, Dmitry Goldgof, Philippe Lambin, Yoganand Balagurunathan, Yuhua Gu, Olya Grove, Hua Wang, Lawrence Hall, Matthew Schabath, Jhanelle Gray, Eduardo Moros, Thomas Dilling, Jongphil Kim, Anders Berglund, Steven Eschrich, Gregory Bloom, John Heine, Andre Dekker, Hugo Aerts, Emmanuel Rios

  5. QUANTITATIVE MRI OF GLIOBLASTOMA RESPONSE

    30 Apr 2014 | Teaching Materials | Contributor(s): Bruce Rosen

  6. Objective Selection of GBM Imaging Features for Clinical Trials

    30 Apr 2014 | Teaching Materials | Contributor(s): Bradley Erickson, Daniel Blezek, Panos Korfiatis, Jian Su, Ross Mitchell

    We focus on identifying MRI features that predict patient survival and response in both low grade and high grade brain tumors.

  7. Multiparametric and Multimodality Quantitative Imaging for Evaluation of Response to Cancer Therapy

    30 Apr 2014 | Teaching Materials | Contributor(s): Eric C. Frey, Michael A. Jacobs, Martin A. Lodge, Hao Wang, Richard L. Wahl

    The overall goal of this U01 is to combine quantitative parameters from multiple modalities, in particular PET/CT, SPECT/CT and MRI, to provide a better prediction or assessment of therapeutic response. We will use different tracers in PET and SPECT and advanced MRI methods. In the project we...

  8. Quantitative MRSI to predict early response to SAHA therapy in GBM management

    30 Apr 2014 | Teaching Materials | Contributor(s): Hyunsuk Shim, Hui-Kuo Shu, Jeffrey J. Olson, Xiaoping P. Hu, Tim Fox, Eduard Schreibmann, Chad A. Holder, Ying Guo, Andrew H. Miller, Daniel Brat, Alfredo Voloschin, Peter Barker, Matthias Holdhoff, Stuart Grossman, Doris Lin, Lawrence Kleinberg, Fausto Rodriguez, Andrew Maudsley

  9. Image Analysis and Performance Metrics Working Group

    30 Apr 2014 | Teaching Materials | Contributor(s): Michael Jacobs, David Newitt

    Information and results regarding the following projects:DCE-MRI Data Analysis ChallengePlatform-Dependent Image Scaling Challenge

  10. Data Acquisition Work Group

    30 Apr 2014 | Teaching Materials | Contributor(s): Paul E. Kinahan, Thomas L. Chenevert

    Information and Results regarding the following projects: Diffusion MRI Demonstration Project: Gradient Non LinearityPET/CT Protocol variations and scanner calibration drift

  11. Clinical Trials Design and Development Working Group

    30 Apr 2014 | Teaching Materials | Contributor(s): Richard L. Wahl, John Buatti, Brenda Kurland, James M. Mountz, Daniel Rubin, Christopher Ryan, Edward Eikman, Elizabeth Gerstner, Frank S. Lieberman

    This poster includes the Goals, Timeline and Specific Project information for the Working Group

  12. Quantitative Volume and Density Response Assessment: Sarcoma and HCC as a Model

    29 Apr 2014 | Teaching Materials | Contributor(s): Lawrence H Schwartz, Binsheng Zhao

    A critical barrier to the development of new cancer therapies is the lack of evidence validating the imaging methods used for patient response assessment. Our project evaluates the ability of improved image analysis techniques, e.g., tumor volume and necrosis fraction, to assess response in...

  13. Quantitative MRI of Prostate Cancer as a Biomarker and Guide for Treatment

    29 Apr 2014 | Teaching Materials | Contributor(s): Fiona Fennessy, Andriy Fedorov, Robert Mulkern, Michelle Hirsch, Mary-Ellen Paplin, Sandeep Gupta, Clair Beard

    Prostate cancer (PCa) remains the most common malignancy and third leading cause of cancer-related mortality in American men with incidence estimated at >450,000 cases per year by 2015. The natural history of PCa is remarkably heterogeneous and still not completely understood. The need for an...

  14. NCI Funding Opporutnity: Innovative Molecular Analysis Technologies (IMAT) Program Overview

    29 Apr 2014 | Downloads | Contributor(s): Tony Dickherber

    This slide deck provides a general overview of the NCI IMAT Program, and discussion of the current portfolio as of Spring 2014.

  15. OmicCircos: A Simple-to-Use R Package for the Circular Visualization of Multidimensional Omics Data

    28 Apr 2014 | Publications | Contributor(s): Hu Y, Chunhua Yan, Hsu CH, Chen QR, Niu K, Komatsoulis GA, Meerzaman D.

    OmicCircos is an R software package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. Such variations can be displayed as scatterplot, line, or text-label...

  16. Data Acquisition Working Group

    21 Apr 2014 | Presentations | Contributor(s): Tom Chenevert, Paul Kinahan

    DA-WG Update on PET-CT and DWI MRI

  17. Image Analysis and Performance Metrics WG - PET/CT Update

    21 Apr 2014 | Presentations | Contributor(s): Jayashree Kalpathy-Cramer, Vyshak Chandra

    IAPM-WG PET/CT Update

  18. Image Analysis and Performance Metrics WG - DW and DCE MRI Update

    21 Apr 2014 | Presentations | Contributor(s): Wei Huang, Tom Chenevert, Vyshak Chandra

    IAPM-WG - DW and DCE MRI Update

  19. Hub Zero Status Update

    21 Apr 2014 | Presentations | Contributor(s): Jayashree Kalpathy-Cramer, Vyshak Chandra

    NCIP Hub, an environment to facilitate collaboration within the Quantitative Imaging Network

  20. Clinical Trials Design, Development, and Outreach Working Group

    21 Apr 2014 | Presentations | Contributor(s): Richard Wahl, John Buatti, Vyshak Chandra

    Clinical Trials Design, Development, and Outreach Working Group Update