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  1. Integrative Cancer Biology Program Datasets

    26 Apr 2016 | Series | Contributor(s): Jonathan Bistline, Michael Reich

    The NCI-ICBP promotes an integrative/systems approach to the study of cancer biology. The Program encourages scientists to study cancer as a complex biological system. Information gained from these studies are used to build reliable and testable predictive computation models of cancer processes...

  2. Breast Cancer Crossword

    20 Nov 2015 | Teaching Materials | Contributor(s): Katelyn Schifano

    This crossword is designed for use in social media as well as patient waiting areas.

  3. Screening for Small Molecules: Target Discovery Against miRNAs for Breast Cancer Treatment

    18 Aug 2015 | Presentations | Contributor(s): Odemaris Narvaez del Pilar

    Breast cancer is one of the leading causes of cancer related deaths and morbidity among women worldwide. Identifying new targets and developing new therapies is very important in order to improve patient outcomes and minimize this health burden. MicroRNAs, a type of non-coding RNA, are potential...

  4. HUBzero: A platform for dissemination and collaboration in Computational Science and Engineering

    07 Aug 2015 | Publications | Contributor(s): Michael McLennan, Rick Kennell

    The HUBzero cyberinfrastructure lets scientific researchers work together online to develop tools. Other researchers can then access the resulting tools using an ordinary Web browser and launch simulation runs on the national Grid infrastructure, without having to download or...

  5. The World of HUBzero

    11 Feb 2015 | Presentations | Contributor(s): Michael McLennan

    This part of a demo/presentation from the Force2015 conference giving you a 9 1/2 minute overview of the HUBzero platform and its capabilities - NCIP Hub is based on the HUBzero platform.[[Youtube(p_hpwoiXvEE,300,200)]]

  6. LBL ICBP50 integrative genomic data

    13 Nov 2014 | Downloads | Contributor(s): Joe Gray, Jonathan Bistline

    From Joe Gray, Lawrence Berkeley National Laboratory.  There are seventeen (17) files in this study: Affymetrix U133A gene expression data (icbp_u133a.gct) Affymetrix U133A gene expression data (ICBP_U133a.zip) Affymetrix splice junction exon-exon data (ICBP_Junction.zip) Affymetrix...

  7. Baylor Residual breast cancer

    13 Nov 2014 | Downloads | Contributor(s): Creighton C, Lewis M, Chang J, Jonathan Bistline

    Residual breast cancers after conventional therapy display mesenchymal as tumor-initiating features.  There are four (4) files included in this study: Sample Annotation (combined_sample_annotation.txt) Gene expression data from CD44+/CD24- cells sorted by flow cytometry (GSE7513.gct) Human...

  8. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...

  9. Tips for creating Standards Group Pages

    22 May 2014 | Teaching Materials | Contributor(s): Denise Warzel

    The Standards Portal offers a way to organize dsicussions and resources related to a set of standards. The organizing construct can be either a community interested in sharing data or using common tools, or by a particular type of standard, for example demographics or biomarkers. An example of a...

  10. Getting Started at the Standards Portal Pilot

    27 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin

    The Standards Portal Pilot is now available! (Click the link for the portal home page.)Why use the standards portal? See more information about its genesis and use cases in a study conducted for the VCDE caBIG community here. If you are participating in the Pilot, please join the...

  11. Standards Portal CRFs Complete View

    19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    This DataView resource page is for the Standards Portal CRFsUse this DataView to browse,search, explore and download the complete set of columns for NCI case report form standards at the Hub. These CRFs were brought to the Hub for clarification, discussion and discovery. They were assembled by...

  12. Standards Portal CDEs Common Data Fields

    19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    This DataView is for the Common Data Fields of the Standards Portal CDEsUse this DataView to browse, search, explore and download the essential set of columns for NCI common data elements standards at the Hub. These CDEs were brought to the Hub for clarification, discussion and discovery. They...

  13. Standards Portal CRFs Common Data Fields

    19 Mar 2014 | Downloads | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    This DataView is for the Common Data Fields of the Standards Portal CRFsUse this DataView to browse, search, explore and download the essential set of columns for NCI case report form standards at the Hub. These CRFs were brought to the Hub for clarification, discussion and discovery. They were...

  14. Why Use the Standards Portal at the Hub?

    19 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Sumudinie fernando, Ann Christine Catlin

    The materials attached to this page were provided by Baris Suzek, who at the time was the Informatics Project Lead at the Innovation Center for Biomedical Informatics at Georgetown University School of Medicine. He conducted a study for the caBIG VCDE community to help clarify some of the...

  15. Standards Portal Vocabulary DataView

    15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    The DataView for terminology referenced/used by the CDEs and CRFs currently contained in the Standards PortalThe DataView on this resource page can be used to browse, search, explore and download the NCI concepts for vocabulary referenced by the CDEs and CRFs uploaded to the Standards Portal....

  16. Standards Portal CDEs Complete View

    15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    This DataView on this resource page is used to explore the Standards Portal CDEsUse the DataView provided on this resource page to navigate, browse, search, explore and download the complete set of columns for NCI common data elements standards at the Hub. These CDEs are brought to the Hub for...

  17. NCI Standard CRFs

    15 Mar 2014 | Teaching Materials | Contributor(s): Denise Warzel, Ann Christine Catlin, Sumudinie fernando

    Working in conjunction with NCI has developed a collection of Standard Case Report Forms (CRFs) for use in developing new protocols. The project and its status are described here. The reuse of sections from standard CRFs helps to ensure that data collected in different studies is compatible and...

  18. Performance Status Scoring : a standards portal resource

    15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel, Angela Kummerow

    The scoring scale used may depend on patient population, disease, study goals and other criteria. Many definitions of the scale scoring do not match the standard.What is Performance Status?Performance status attempts to quantify the general well-being of cancer and other patients. The score...

  19. Adverse Events Terminology Standards, Data Elements and Case Report Forms

    15 Mar 2014 | Teaching Materials | Contributor(s): Sherri de Coronado, Ann Christine Catlin, Sumudinie fernando, Denise Warzel

    Standards for coding, naming and grading adverse events (AEs) in cancer clinical trials include both cancer-focused and broader systems that all result from collaboration among academic, governmental, and pharmaceutical industry clinical investigators. They are all based on the need for...

  20. TCGA Common Data Elements

    15 Mar 2014 | Teaching Materials | Contributor(s): Ann Christine Catlin, Sumudinie fernando, Denise Warzel

    TCGA Common Data ElementsTCGA version 2.6 CDEs are the standard elements that were used in validation of clinical data in the TCGA 2.6 data files. The data files are available for download at the Data Matrix. This resource page at the NCIP HUB presents the CDEs for easy search and discovery....