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Multiparametric and Multimodality Quantitative Imaging for Evaluation of Response to Cancer Therapy

By Eric C. Frey1, Michael A. Jacobs1, Martin A. Lodge2, Hao Wang2, Richard L. Wahl1

1. The Russell H. Morgan Department of Radiology and Radiological Science, and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, PI 2. The Russell H. Morgan Department of Radiology and Radiological Science, and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University

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Abstract

The overall goal of this U01 is to combine quantitative parameters from multiple modalities, in particular PET/CT, SPECT/CT and MRI, to provide a better prediction or assessment of therapeutic response. We will use different tracers in PET and SPECT and advanced MRI methods. In the project we will develop, optimize and validate quantitative imaging-based multiparametric response metrics.

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Researchers should cite this work as follows:

  • Eric C. Frey; Michael A. Jacobs; Martin A. Lodge; Hao Wang; Richard L. Wahl (2014), "Multiparametric and Multimodality Quantitative Imaging for Evaluation of Response to Cancer Therapy," https://ncihub.cancer.gov/resources/299.

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