=Upcoming activities= 8/6/2021: Discussion about patient sampling for HTT pivotal study * Lead: Victor Garcia is a new FDA fellow with an MD (board ready) and a Clinical Informatics Fellowship. * contact Katherine Elfer (Katherine.Elfer@fda.hhs.gov) or Brandon Gallas (Brandon.Gallas@fda.hhs.gov) to join the conversation 8/8/2021: Presentation at the American Statistical Society Joint Statistical Meetings * “Pathologist Agreement from Quantitative Measurements: a Pilot Study” * In coordination with this presentation and the corresponding proceedings paper, we intend to make public a !GitHub repository (name "HTT") with an R data package containing the pathologist annotations. * [Presentation:JSMPathologistAgreementfromQuantitativeMeasurements:aPilotStudy LINK to Full Presentation Information] * [https://ww2.amstat.org/meetings/jsm/2021/onlineprogram/AbstractDetails.cfm?abstractid=318980 LINK to Conference Program] 8/12/2021: FDA Annual Summer Student Scientific Poster Day * 9:30 - 11:30am EDT * Two Posters from our summer interns: * Title 1: Developing a controlled workflow for clinical studies to collect pathologist annotations * Title 2: Communication Methods and Workflows to Develop and Implement High Throughput Truthing of Pathologist Annotations as a Reference Standard for Validating Artificial Intelligence in Digital Pathology. * [Presentation:ORISESummerStudentScientificPosterDay2021 Link to full abstracts] *[https://collaborationcqpub1.fda.gov/content/connect/c1/7/en/events/event/shared/default_template/event_registration.html?sco-id=241882471 Link to Register for full FDA Webcast & Poster Event] =Recent accomplishments= 7/2021: Statistical Methods Presentation * Si Wen, Statistician FDA/CDRH/OSEL/Division of Imaging, Diagnostics, and Software Reliability * Title: Quantitative Agreement Analysis for HTT Pilot Study Data * Presentation video and !GitHub repo with methods coming and will be linked [Presentation:WenQuantitativeAgreementAnalysisforHTTPilotStudyData HERE] * Related manuscript: Preprint on [https://arxiv.org/abs/2107.08891 arXiv - 2107.08891]. It has been submitted to Statistics in Biopharmaceutical Research. 7/2021: Shipped eeDAP system to Yale for microscope-mode data collection * [https://github.com/DIDSR/eeDAP eeDAP Github Repo] * Looking for pathologists to provide annotations * Upgraded eeDAP hardware for speed * Resolved third-party software version conflicts (Bioformats, Java, and Matlab - [https://github.com/DIDSR/eeDAP/issues/89] ) 7/2021: We have executed two research collaboration agreements (RCA) for slide sourcing. * [HTTAdminRCA:ResearchCollaborationAgreements LINK to RCA Abstracts] 6/2021: Hired six summer research assistants to support related research