Collections

PDX Portal: A compendium of Patient Derived Xenograft (PDX) models

Patient Derived Xenograft (PDX) models for cancer research are created by the implantation of human cells and tumor tissue into immune compromised mouse hosts. PDX models provide a platform for in vivo cancer biology studies and pre-clinical cancer drug efficacy testing. The current state of the art mouse host is the "NOD-SCID-Gamma2" (NSG) mouse. NSG mice lack mature T and B cells, have no functional natural killer cells, and are deficient in both innate immunity and cytokine signaling.

The PDX Portal allows users to search for Patient Derived Xenograft models created at The Jackson Laboratory.

0 posts

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Carol J Bult

Mouse Models of Human Cancer: The Mouse Tumor Biology Database

 

The Mouse Tumor Biology (MTB; http://tumor.informatics.jax.org) database is a unique online compendium of mouse models for human cancer.

MTB provides online access to expertly curated information on diverse mouse models for human cancer and interfaces for searching and visualizing data associated with these models.

Use MTB to find:

  • characteristic cancer incidence for inbred strains of mice
  • genetically modified mice used to model human cancer
  • mouse models for genes commonly mutated in human cancers

0 posts

Profile picture of Carol J Bult

Carol J Bult

KOMP2 and IMPC knockout mice for the oncology research community

The International Mouse Phenotyping consortium funded in large part by the The KOMP2 Common Fund is producing and characterizing a knockout out mouse strain for every protein coding gene. Each strain is tested by a high-throughput phenotyping pipeline to assess physiological characteristics across a wide range of biological systems. By assessing the phenotypes that results when a gene is switched off, we hope to gain new insights into gene function. Here we will gather posts about knockout mouse strains that might be of interest to the oncology community.

4 posts

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Jeremy Mason

Media Links

UPR/MDACC Partnership MD/PhD trainees' media links

2 posts

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Sherri De Jesus

Poster Presentations

Posters presented by UPR/MDACC MD/PhD trainees during their summer research experience, tutorials, or lab work.

12 posts

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Sherri De Jesus

Publications

This collection includes published articles by UPR/MDACC MD/PhD trainees during and after their training within the Program.  All trainee names are bolded. The privacy setting for this group is public.

20 posts

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Sherri De Jesus

UPR/MDACC Grants and Supplements (Trainees and Junior Faculty - excluding MD/PhD trainees)

This collection contains both direct and indirect grants from trainees and junior faculty that have resulted from the UPR/MDACC Partnership for Excellence in Cancer Research. The privacy setting for this collection is public.

3 posts

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Sherri De Jesus

Workshops

2 posts

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Julia Puzak

NIH BD2K

4 posts

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Julia Puzak

NCIP Hub News

A collections of news and blog posts on NCIP Hub.

6 posts

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Ishwar Chandramouliswaran

ITCR Training Assets

Lectures and  courses on-line

18 posts

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Ishwar Chandramouliswaran

News and info

8 posts

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Brandon D. Gallas

Stories of Genome Sequencing in Medical Diagnoses

Stories and articles of the use of genome sequencing in medical diagnoses of rare diseases.  

16 posts

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Tricia Lu

Webinar Powerpoints

This is a collection of selected ppts that have been presented at our weekly Webinar.

1 posts

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Neil Hubbard

National Cancer Institute Data Collections

Links to NCI data portals, sites, and collections

17 posts

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Tricia Lu

Cancer Organizations

A collection of cancer charities, funds, non-profits, non-governments, and other organizations.

87 posts

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Tricia Lu

SCIENCE

Interesting science tidbits.

3 posts

Profile picture of Ishwar Chandramouliswaran

Ishwar Chandramouliswaran